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Clomipramine information

Why you may need to use Clomipramine

Clomipramine is a prescription tricyclic antidepressant medicine you may need to be taking if you have obsessive-compulsive disorder and can't get some of its symptoms under control. The symptoms Clomipramine usually works for include repetitive actions or recurrent thoughts or feelings known as obsessions. There may be some other possible uses for Clomipramine because of its mechanism of action (it corrects the imbalance of chemicals in the brain), but this always has to be discussed with a qualified health care professional to make sure your treatment is safe and successful. You must not start Clomipramine treatment if you have a recent history of a heart attack of have recently used any MAO inhibitors, such as rasagiline, isocarboxazid, selegiline, tranylcypromine or phenelzine. You must not take Clomipramine if you have ever been allergic to this medicine or similar drugs like trimipramine, desipramine, amoxapine, nortriptyline, protriptyline, clomipramine or imipramine.

Before Clomipramine treatment can be started

Talk to your doctor before you take Clomipramine for the first time, as there may be some other conditions that require a dose adjustment or any changes made to your treatment schedule. You will have to inform your doctor of any medical issues from the list below, as well as any other ones you think are important to mention and take into consideration: bipolar disorder, adrenal gland tumor, stroke, or seizures, heart disease, problems with urination, kidney or liver disease, overactive thyroid, a history of heart attack or stroke, schizophrenia, glaucoma or a history of seizures.

How is it best to take Clomipramine?

Taking Clomipramine right is the best way you can benefit from the treatment. You will need to take every dose with a full glass of water at the same time. Use Clomipramine regularly for maximum benefits. Some 4 weeks may be required for some patients to notice the first improvement. You need to talk to your doctor if after this period you do not get an improvement, and your symptoms persist. Make sure you always let your doctor know if there is anything you are not clear about. If you are younger than 24, your doctor will most probably want to see your regularly for the first 12 weeks of the treatment. Patients from this age group are more likely to develop suicidal thoughts and other symptoms, although this is not a common occurrence. You have to let your doctor know right away if you get aggressiveness, impulsiveness, agitation, panic attacks, hostility, restlessness, worsened depression, irritability, trouble sleeping, hyperactivity, mood or behavior changes, anxiety or suicidal thoughts.

What side effects can occur because of Clomipramine?

Make sure you contact your health care provider as soon as possible if you notice such serious side effects of Clomipramine as heavy feeling, confusion, fast or uneven heartbeats, sudden headache, problems with vision or speech, sudden numbness or weakness, chest pain, pain spreading to the arm or shoulder, feeling light-headed, sweating, fever, confusion, pale skin, general ill feeling, fainting, muscle stiffness, easy bruising or bleeding, balance problems, urinating more than usual, sweating or unusual weakness. The serious side effects mentioned are not too likely, but you still have to keep in mind their possibility and avoid continuing the treatment if they appear at any point of it. You can carry on with taking Clomipramine even if you get a few mild side effects of this medicine. Such mild side effects of Clomipramine as nausea, blurred vision, vomiting, drowsiness, decreased sex drive, blurred vision, diarrhea, increased sweating, constipation, weight changes, loss of appetite, trouble concentrating, unpleasant taste in the mouth, dry mouth, stomach pain, impotence, feeling anxious, sleep problems, dizziness, nightmares, increased appetite or restlessness, are most likely to go away soon on their own. You will not need to tell your doctor about them only if they get more severe or affect your everyday life in any way.

Which other medications interact with Clomipramine?

Any drugs you are using must always be discussed with a qualified health care professional in advance. This is important to prevent interactions that are possible otherwise. You will always have to let your doctor know about any of the following prescription or over-the-counter drugs if you are using them at the moment: fluvoxamine, anti-psychotic medications, heart or blood pressure medications, pain medications, phenytoin, cold medicine, propafenone, cimetidine, methylphenidate, sertraline, medicine for seizures, citalopram, escitalopram, quinidine, flecainide, guanethidine, warfarin, muscle relaxers, fluoxetine or paroxetine.

Is Clomipramine likely to harm an unborn child?

You will have to let your doctor know if you are pregnant or breastfeeding at the moment of starting your treatment. It's very important to make sure you report the fact of being pregnant or breastfeeding, as there is a chance Clomipramine may be harmful for your child. Your doctor will probably tell you not to take Clomipramine and breastfeed, so you may need to stop breastfeeding.

Clomipramine overdose

An overdose of Clomipramine can be very dangerous and even lead to death in cases you take too much. If you overdosed Clomipramine, seek emergency medical help, especially if you also have such symptoms as extreme drowsiness, fast or uneven heart rate, blue lips or fingernails, fainting, swelling, muscle stiffness, feeling light-headed, vomiting, blurred vision, increased or decreased urination, shortness of breath, sweating, confusion, agitation, coma or seizure.

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