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Cymbalta information

Basic info on Cymbalta

Cymbalta was developed in the late 1980s as an SNRI medication, which stands for serotonin-norepinephrine reuptake inhibitor. What this means is that this medication inhibits the reuptake of serotonin and norepinephrine, which are two important chemicals in the brain. By increasing the levels of these chemicals, Cymbalta brings many beneficial effects in different cases, most commonly mood disorders. There are many different uses for this medication and the most common ones are major depressive disorder, stress urinary incontinence and generalized anxiety disorder. There have been many studies that have shown that Cymbalta should be the first-line medication in the treatment of generalized anxiety disorder as it is well tolerated even with prolonged use. Cymbalta can also relieve pain in cases of diabetic peripheral neuropathy and other uses for this medication include fibromyalgia, chronic fatigue, interstitial cystitis as well as muscoskeletal pain, especially in cases of chronic lower back pain and osteoarthritis. These uses are mainly due to the properties of Cymbalta that have an effect on the pain that is characteristic of these conditions.

Discuss using Cymbalta with your doctor

This is the most important thing to do if you wish to make sure you will experience a beneficial and risk-free Cymbalta treatment. You need to discuss your medical history and your current state of health with your doctor who will then decide if it is safe for you to take Cymbalta and what regimen would best suit your condition. You must under no circumstances fail to mention if you have been using any MAO inhibitors within 14 days of the start of your Cymbalta treatment. MAO inhibitors stay for as long as 14 days in the system and if the Cymbalta is taken while there are still even traces of MAOIs in the system, a severe interaction is possible that can even be lethal. Furthermore, if you are allergic to Cymbalta or if you have uncontrolled or untreated glaucoma, you should also not take Cymbalta. Some other conditions are also affected by Cymbalta and you need to report those to your doctor as well. Like for example any kidney or liver diseases, epilepsy or other seizure disorders, glaucoma, blood clotting or bleeding disorders, bipolar disorder or if you have a history of suicidal thoughts or drug abuse. Pregnant women and breastfeeding women should only take Cymbalta if specifically instructed to do so by their doctor. Otherwise, the potential risks outweigh the benefits and the risk is just too high for the health of the fetus or the nursing child. Cymbalta should also not be given to anyone under the age of 18, while the elderly might experience more side effects of Cymbalta.

Once the Cymbalta treatment starts

Cymbalta, like all other antidepressants can cause certain suicidal thoughts in patients who have just started using them, especially if the patients are under the age of 24. This happens very rarely, but your doctor will still need to monitor your progress and regimen closely for the first couple of months of the treatment. Also, both you and the people around you need to be alert to any changes for the worse in your behavior or mood. This includes suicidal thoughts, more severe depression, hyperactivity, restlessness, aggressiveness, hostility, agitation, irritability, impulsiveness, troubles sleeping, panic attacks or bouts of anxiety. It is very important that you adhere to the prescribed regimen as otherwise you risk developing serious side effects. It is also important to gradually discontinue your Cymbalta regimen as you might otherwise experience withdrawal symptoms. Your doctor can help you with this. Furthermore, keep in mind that it may take up to four weeks for Cymbalta to start having effect on your health. Also, be aware that Cymbalta may impair your reactions and your thinking and if you experience these sedative side effects, you need to refrain from driving or operating machinery.

Possible Cymbalta side effects

Cymbalta is usually well tolerated and the side effects that are experienced are in large majority of cases the less serious ones like dry mouth, drowsiness, tiredness, mild nausea, loss of appetite and constipation. However, there is also a slight possibility of some serious side effects that you have to consult your doctor about. These include jaundice, dark urine, loss of appetite, itching, nausea, fainting feeling, hallucinations and other psychological symptoms that we have mentioned before, tremors, uneven heartbeats, confusion, sweating, high fever, rigid muscles, unusual bleeding and bruising, difficulties urinating, shallow and interrupted breathing, seizures, loss of coordination, unsteadiness, weakness, memory issues, troubles concentrating, severe headaches.

Medications that interact with Cymbalta

These are just some of the possible interactions with Cymbalta: warfarin, cimetidine, diuretics, fluvoxamine, linezolid, lithium, St. John's wort, tramadol, tryptophan, certain antibiotics, almotriptan, sumatriptan, naratriptan, other antidepressants.

How to deal with a Cymbalta overdose

In case of a Cymbalta overdose you must seek emergency medical help and let them know of any symptoms such as agitation, fever, loss of coordination, vomiting, convulsions, lightheadedness, hallucinations, overactive reflexes, extreme drowsiness, diarrhea, fast heartrate and fainting.

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