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Danocrine information

What is Danocrine Prescribed For?

Danocrine is the brand name for the active drug Danazol. It was first approved by the FDA in 1970s for treating endometriosis, a condition commonly occurring in females in which uterine-like cells grow outside of the womb. This can lead to painful menstruations and infertility. Because of risk of side effects, Danocrine is now rarely prescribed for endometriosis except in cases in which the condition is so severe it results in infertility or pain. Danocrine is now commonly prescribed for treating menorrhagia (a condition in which menstruation lasts abnormally long), fibrocystic breast disease (cysts in female breasts), or hereditary angioedema (extreme swelling to the dermis). Additionally, Danocrine is prescribed for treating abnormal breast growth in male patients and early puberty in female children.

How Does Danocrine Work?

Danocrine is made from a type of synthetically modified testosterone. Because testosterone is the male hormone, it can inhibit certain hormones predominantly found in females. When these female hormones are decreased, certain conditions are improved, such as prolonged menstruation or development of uterine cells. Danocrine also can increase levels of certain proteins of the immune system, thus treating angioedema.

How to take Danocrine

Danocrine is typically available in capsule forms. The dosage amount and instructions will vary per patient based on condition and other factors such as age. Always take it exactly as prescribed by your doctor. Typical dosages of Danocrine are between 50 to 400 milligrams, usually taken two or three times per day. Duration of treatment is usually three to six months though this varies based on condition and response to treatment. To get the best results, take Danocrine at evenly-spaced intervals of time and the same time every day. Always swallow the capsules whole without chewing or breaking them. If you cannot swallow the medicine, consult your doctor for advice on how to take Danocrine.

Danocrine Side Effects

While taking Danocrine, the following side effects are common: changes in weight, skin breakouts, feeling flush, perspiration, change in voice, increased or unusual growth of hairs, vaginal discomfort, or diminished size of breasts. These side effects are usually not serious but contact your doctor if they persist or are bothersome. In event that you experience any of these unlikely adverse effects, contact your doctor at once: inflammation to extremities, unusual menstruation change (such as missing your menstruation or spotting between periods), or unusual moods. Though it is rare for patients to have a serious allergy to Danocrine, immediately get medical assistance if you have any of these signs of reaction such as: hives, rashes, inflammation to oral/facial areas, or feel like you cannot breathe.

Warnings about Danocrine

In rare cases, taking Danocrine can cause severe blood clotting or pressure inside the brain cavity. Immediately get medical help if you have any of these serious adverse effects while taking Danocrine: brown urine, chronic or severe nausea, skin or eyes turn yellowish, severe mood changes, chronic or severe headaches, becoming weak/numb on only one side of the body, sudden vision changes, or difficulties with speech.

Who Should Not Take Danocrine?

Before you begin treatment with Danocrine, you should inform your doctor about your complete medical history. It may not be safe for you to use this medicine if you have certain health problems, especially the following: allergies, cardiovascular problems, blood vessel or arterial problems, hypertension, high levels of blood fats, cancer, impaired kidneys or liver, blood-related disorders, migraines, disorders causing seizures, or menstruation problems. This medicine should never be taken by pregnant women. Before you have any medical surgery, including dental surgeries, make sure that your doctor or dentist knows you are using Danocrine.

Danocrine during Pregnancy and Breastfeeding

Danocrine is FDA pregnancy category X which means that the drug is known to cause harm to unborn children. Do not take Danocrine if you are pregnant. Before starting treatment, you should have a negative pregnancy test. Treatment in females is often started during menstruation as an added precaution to ensure the patient is not pregnant. While taking Danocrine, women of childbearing age should use two reliable forms of birth control. If you think you have become pregnant while taking Danocrine, immediately contact your doctor. It is currently unknown if Danocrine can be passed to a nursing infant through breast milk and cause harm. It is highly recommended against breastfeeding while using Danocrine.

Interactions with Danocrine

Before you begin taking Danocrine, be certain your doctor knows of all medicines, drugs and herbal treatments you may take because a serious interaction could occur, especially with the following: blood thinners, anticonvulsants, some high cholesterol medicines, immunosuppressant drugs, or mood-altering drugs (such as antidepressants). This is not a complete list of interactions so be sure to discuss risk of interactions with your doctor.

Missed Doses of Danocrine

If you miss your dosage of Danocrine, take it as soon as possible. However, if it is already near the time of your next planned dosage, then omit the missed dosage and resume your planned dosing schedule. Never take an extra dosage of Danocrine to compensate for a missed dosage.

Overdoses of Danocrine

Taking too much Danocrine could result in a serious overdose. Signs of an overdose may include: jaundice, extreme abdomen pains, or darker urine. If you think an overdose of Danocrine has occurred, immediately seek emergency medical treatment or contact your area's poison control helpline.

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