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What is Desyrel and Why is it Prescribed?

Desyrel is a brand name for the active drug Trazodone. It is a type of antidepressant called a Serotonin Antagonist and Reuptake Inhibitor (SARI). These types of antidepressants work by provoking the brain to produce more of the neurotransmitter serotonin. It also hinders the way serotonin and the neurotransmitters dopamine and norepinephrine are reabsorbed after they are released. Since these neurotransmitters are responsible for creating a feeling of well being, Desyrel is effective in treating depression. It is also effective in treating anxiety disorders and manic depression. In some countries, Desyrel is approved for treating sleeping problems such as insomnia.

How to Take Desyrel

Your doctor will prescribed Desyrel to you based on your condition and how you respond to treatment. Always take Desyrel exactly as it was prescribed. It is common for doctors to initiate treatment at low doses to reduce risk of side effects and monitor patients' responsiveness to the medicine. Then, dosage amount may be increased gradually as needed. For once daily treatment, it is best to take Desyrel before going to sleep. For twice daily treatment, take one of the doses before going to sleep. Desyrel is usually taken after meals. It could take up to one month before the full benefits of Desyrel are evident.

Adverse Effects of Desyrel

While taking Desyrel, the following adverse effects are common but usually not serious: gastrointestinal disturbances, changes to bowel movements, dizzy spells, blurry eyesight, weight changes, headaches, muscular aches, decrease salivation, cold-like symptoms, or changes to libido/sexual abilities. Inform your doctor if these adverse effects are long lasting or bothersome. Inform your doctor at once if you have any of these uncommon but serious adverse effects: uncontrollable body movements, bad dreams, hear ringing sounds, difficulties with urination, bloody urine, symptoms of an infection, difficulty breathing, or severe abdomen/stomach pains. In event that you have any of these rare but serious adverse effects, immediately seek medical attention: signs of a heart attack (chest pain which may radiate outwards, sudden changes to vision/hearing/mental state, or slurred speech), seizure, loss of consciousness, an erection which lasts longer than four hours or is painful (priapism), or signs of a serious allergic reaction (skin irritation, troubles breathing, or inflammation to facial/oral areas).

What to Know before You Take Desyrel

Even though antidepressants such as Desyrel are prescribed for treating depression, in rare cases they can actually cause a worsening of condition. This is more likely in patients who are under the age of 25. Before taking Desyrel, talk about the risks of taking antidepressants. If you experience a worsening of your condition or symptoms of a new mood disorder, immediately contact your doctor.

Who Should Not Take Desyrel?

Patients with certain medical problems may not be able to safely take Desryel or may require special dosing instructions or monitoring for adverse effects. Make sure your doctor knows your complete medical history before you begin treatment, especially if you have any of these conditions: allergies, have had priapism, cardiovascular problems, psychiatric problems (especially bipolar disorder), impaired kidneys, hypertension, hypotension, or liver problems. Desyrel is FDA category C for pregnancy which means it could cause harm to an unborn baby. However, mental health disorders should not go untreated. Only use Desyrel during pregnancy if your doctor determines it is absolutely necessary. You may be weaned off the drug during the last trimester. Do not take Desyrel while breastfeeding without first consulting your doctor.

Precautions while Taking Desyrel

Desyrel could cause adverse effects which impair your eyesight or alertness. This could make it dangerous to perform certain tasks which require these qualities, such as driving a car. Until you are certain that Desyrel has not impaired your ability to do so, avoid all such activities which may be dangerous. Elderly patients should take caution to avoid accidents resulting from falls as Desyrel may cause dizziness.

What Can Interact with Desyrel?

Before you take Desyrel, make sure that your doctor knows of all medicines, drugs (including illicit drugs) and herbal treatments which you may use because a serious interaction could occur. Especially be certain your doctor knows if you take any of these: benzodiazepine-type drugs, sibutramine, psychiatric medications, drugs which may increase serotonin levels (including illicit drugs like MDMA), HIV/AIDS medications, blood thinners, medicine against fungal infections, antibiotics, anticonvulsants, St. John's wort, hypertension medications, monoamine oxidase inhibitors, or drugs which may cause drowsiness (such as an antihistamine, muscle relaxers, narcotics, sleeping pills or many cough/cold medications). Before having any medical operation which requires a anesthetic, be sure your doctor or dentist knows you are taking Desyrel because an interaction may occur.

Missed Doses of Desyrel

If you miss your scheduled dosage of Desyrel, take it as soon as possible. However, if it is already near the time of your next dosage, then omit the missed dosage and resume your regular dosing schedule. Do not take an extra dosage to compensate for any missed dosage.

What to do for an Overdose of Desyrel

Taking too much Desyrel could result in a serious overdose. Signs of an overdose onf Desyrel may include: long-lasting or painful erection, changes to pulse, extreme lethargy, lightheadedness, vomiting, respiratory difficulties, or convulsions. If you think that an overdose has occurred, immediately seek emergency medical treatment or call your area's poison control helpline.

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