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Eldepryl information

What is Eldepryl and Why is it Prescribed?

Eldepryl is a brand name for the active drug Selegiline Hydrochloride. It belongs to a group of drugs called monoamine oxidase (MAO) inhibitors. MAO is a type of enzyme naturally occurring in the body which is involved in the process of breaking down the neurotransmitter dopamine. It is believed that low levels of dopamine may account for the spasm-like symptoms of Parkinson's disease. By taking Eldepryl, the process in which dopamine is broken down is inhibited and more of the neurotransmitter is available. This makes Eldepryl an effective treatment for many of the symptoms of Parkinson's disease such as "on-off" muscular movements and tremors. Eldepryl will not, however, cure Parkinson's disease. It is often used in combination therapy with other drugs for managing symptoms of Parkinson's disease.

How to take Eldepryl

Eldepryl tablets are usually prescribed to be taken two times per day, once at breakfast and once during the midday meal. Swallow Eldepryl tablets whole without chewing or breaking them. The disintegrating tablets of this drug (marketed under the brand name of Zelapar) are usually only taken once before the first daily meal and without any form of liquids. Never touch the disintegrating tablets with moist or wet hands and do not remove them from their packaging until you are ready to take them. The disintegrating tablets should completely dissolve on your tongue, not swallowed whole. Do not consume any foods or drinks for a minimum of five minutes after taking disintegrating Eldepryl. Follow all instructions about taking Eldepryl with other medications. Do not abruptly stop taking Eldepryl as it could result in a worsening of your condition. Follow all instructions on foods to avoid while taking Eldepryl.

Potential Side Effects of Eldepryl

While taking Eldepryl, it is common to experience these unserious adverse effects: dizzy spells, abdomen pains, decreased salivation, feeling nauseous, stomachache, difficulties sleeping, and headaches. Inform your doctor if these adverse effects are persistent or severe. Inform your doctor at once if you have any of these serious adverse effects: loss of conscious, loss of equilibrium, unusual change of mood or mental state, worsening of condition, change in libido/sexual abilities, inflammation to feet or legs, troubles with urination, unexplained weight gain, become bruised easily, or blood vomit or stool (may be dark colored). Taking Eldepryl in rare cases may lead to a serious onset of hypertension which could be deathly. Get medical help at once of if you have any of these adverse effects: changes to heart rate, pains in chest, severe headaches, severe nausea, neck rigidity/pains, unusual sweats, dilated pupils, change to eyesight, or abruptly becoming sensitive to light. It is rare for patients to have serious allergies to Eldepryl but get immediate medical help if you have any signs of a reaction such as: hives, rashes, troubles with how you breathe, or inflammation to facial/oral areas.

What to Discuss with Your Doctor before taking Eldepryl

Before you begin treatment with Eldepryl, make sure you discuss your complete medical history with your doctor because it may not be safe for you to take this drug. Particularly be sure your doctor knows if you have: allergies, hypertension, history of strokes, tumors, cardiovascular problems, frequent or severe headaches, ulcers, disorders related to bleeding, are diabetic, personal/family history of psychiatric disorders, liver problems, phenylketonuria, or hyperthyroidism. Eldepryl is in the FDA category C for pregnancy which means it is unknown what effects the drug could have on an unborn child. Do not take Eldepryl during pregnancy unless your doctor determines it is absolutely necessary. Do not take Eldepryl while breastfeeding without first consulting your doctor.

Precautions while taking Eldepryl

This medicine may cause side effects which could impair your vision or alertness. Until you are certain that Eldepryl has not had these effects on you, avoid all activities which could be dangerous with impaired alertness or vision, such as driving a car. Before you have any medical operation, make sure that your doctor or dentist knows you are taking Eldepryl. You may be required to temporarily stop treatment before the operation.

Interactions with Eldepryl

If you take certain medicines, drugs or herbal products with Eldepryl, it could cause a serious interaction which may even be fatal. Eldepryl and other drugs can remain in your body even after treatment has stopped. So, you may need to wait several weeks after ceasing treatment to take Eldepryl or any drug which could interact with it. Make sure your doctor knows of all medicines, drugs (including illicit drugs) and herbal treatments you have recently used or may use, especially of the following: antidepressants, psychiatric drugs, MDMA, "acid", mescaline, stimulating drugs (such as any amphetamine or cocaine), any supplement, other MAO inhibitors, weight-loss drugs, carbamazepine, nafcillin, Phenobarbital, rifampin, or some cough/cold medicines.

Foods to Avoid while taking Eldepryl

Follow all instructions about foods to avoid while taking Eldepryl as instructed by your doctor because a serious case of hypertension could occur. Do not eat any foods which have high levels of tyramine, such as: meats which have been dried/pickled/fermented, draft beers, unpasteurized beers, aged cheese, many supplements, many cough/cold medicines, soya products, fava beans, sauerkraut, or products with high concentrations of yeast (such as many instant soups and flavorings).

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