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Tramadol/Acetaminophen information

Tramadol/Acetaminophen: Description and Indications

The combination of Tramadol and Acetaminophen is prescribed for short-term treatment of pain. Though Tramadol/Acetaminophen is available in many formulations from various manufacturers, the most well-known comes under the brand name of Ultracet which contains 37.5 mg of Tramadol and 325 mg of Acetaminophen. The drug Tramadol is a synthetically-made opiate which is similar to Codeine as a potent narcotic pain killer with addictive properties. Acetaminophen is a less-potent pain killer of the NSAID group. A drug synergy forms when these two drugs are combined together, thus increasing the effectiveness of both. Acetaminophen also discourages recreational use of the drug for its opiate properties and prevents patients from developing high tolerance levels.

Tramadol/Acetaminophen Dosage and Indications

Tramadol/Acetaminophen is typically taken on an as-needed basis for treating pain. The medicine will be most effective if it is taken at the immediate onset of pain, not once the pain has been allowed to peak. Unless otherwise advised, you may take Tramadol/Acetaminophen without regards to meals. Typically, Tramadol/Acetaminophen comes in strengths of 37.5 mg Tramadol/325 mg Acetaminophen. In this formulation, you should never take more than 8 dosages in a period of 24 hours. Patients with impaired kidneys, other health problems, or using certain other medications may have lower daily dosing limits. Do not take more than one dosage at a time and follow instructions about how much time should be between dosages (typically 4-6 hours). Typically, Tramadol/Acetaminophen should not be used for longer than 5 days at a time. If you have chronic pains, then you may be given other medications and instructed only to use Tramadol/Acetaminophen for breakthrough pain relief. Always take Tramadol/Acetaminophen exactly as it was prescribed by your doctor.

What to Know before you take Tramadol/Acetaminophen

The drug Tramadol is a type of opiate. As with other opiates, it is possible to develop a tolerance to Tramadol. That means your body can adjust to the drug's effects and it will no longer be effective in you at standard dosing amounts. Tramadol can also cause dependency (addiction), a condition in which your body adjusts so that the drug is needed in order for your body to function normally. Dependency results in withdrawal effects when treatment is stopped. Some possible Tramadol withdrawal effects include: mood changes, perspiration, nausea, insomnia, muscular spasms, and cold-like symptoms. If Tramadol/Acetaminophen becomes ineffective in treating your pain, you have cravings for the drug, or you experience any withdrawal symptoms, immediately contact your doctor. Never take Tramadol/Acetaminophen for longer than prescribed by your doctor or in higher dosage amounts. Taking too much Acetaminophen could result in serious or even life-threatening liver damage amongst other problems.

Potential Adverse Effects from Tramadol/Acetaminophen

When initiating treatment with Tramadol/Acetaminophen, it is common for patients to experience these adverse effects: feeling nauseous, inability to pass bowels, becoming woozy, fatigue, or perspiration. Tell your doctor if these effects are particularly bothersome or get worse. Get in touch with your doctor right away if you have any of these adverse effects: unusual moods, severe pains in stomach/abdomen, or troubles urinating. Though rare when used as prescribed, Tramadol/Acetaminophen may lead to serious health problems including liver damage and serotonin syndrome (a condition in which there is too much serotonin in the brain). Immediately get emergency medical assistance if you have any of these serious adverse effects while taking Tramadol/Acetaminophen: darkish urine, chronic nausea/stomach pains, jaundice, becoming abnormally restless (physically or mentally), delusions, unusual fever, losing coordination, rapid pulse, muscular spasms, respiratory depression, severe lethargy, deep sleeps from which you have trouble awakening, seizures, losing consciousness, or symptoms of an allergic reaction.

Tramadol/Acetaminophen Contraindications

Do not take Tramadol/Acetaminophen without first telling your doctor about your complete health history. It could be dangerous for you to use this medicine or you may be required to follow special dosing instructions or be monitored for adverse effects. The following conditions could be contraindicated for Tramadol/Acetaminophen: allergies, respiratory problems, brain damage/disorders, impaired kidneys, liver damage, psychiatric problems, personal/family history of drug abuse, gastrointestinal problems, trouble with urination, surgery, pregnancy, and breastfeeding.

Interactions with Tramadol/Acetaminophen

Do not take Tramadol/Acetaminophen without first telling your doctor of all drugs or treatments you may use. A severe interaction could occur including altering the way either drug works or increasing the chances of serious adverse effects. The following are just some of the substances which may interact with Tramadol/Acetaminophen: narcotics, other pain killers, arthritis medicines, MAO inhibitors, antidepressants, lithium, MDMA ("X"), triptan-type drugs, psychiatric medicines, antiviral drugs, medications for migraines, medicine for fungal infections, antibiotics, or anticonvulsants. Avoid consuming alcohol while taking Tramadol/Acetaminophen as it can severely increase the risk of serious side effects including liver damage and lethargy.

What to Do for a Tramadol/Acetaminophen Overdose

Never take more Tramadol/Acetaminophen than recommended as a serious or life-threatening overdose could take place. Symptoms of overdose may include: respiratory depression, sluggish/erratic pulse, fainting, coma, or seizures. If you think that you or someone else has taken too much of this medication, then immediately get emergency medical treatment or contact your local poison control center. Do this even if there are no symptoms of overdose.

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